Content

Reviewed By
Phillip Azouz, MD
Written by
Phillip Azouz, MD
Published
October 3, 2025
Updated
October 16, 2025

Starting a GLP-1 weight loss program can feel exciting — and maybe a little confusing at first. Here’s what your semaglutide dosing journey looks like, step by step, so you know exactly what to expect.

Why Semaglutide Dosing Increases Gradually

Semaglutide is taken once a week to help regulate appetite and support weight loss. To minimize side effects and help your body adjust, your provider starts you at a low dose and gradually increases it every few weeks.
This gradual approach helps reduce nausea, improves tolerance, and ensures your results are both comfortable and sustainable.

Your Typical Dosing Schedule

Note: Exact dosing may vary depending on your provider’s guidance.

Month Weekly Dose (mg) Units (for reference) What to Expect
Month 1 0.2 mg weekly 20 units Your starter dose. Appetite may begin to decrease, and your body starts adjusting.
Month 2 0.25 mg → 0.5 mg weekly 10 → 20 units You may notice smaller portions and steadier appetite control.
Month 3 1.0 mg weekly 40 units More consistent weight loss and appetite regulation.
Month 4 1.5 mg → 1.75 mg weekly 60 → 70 units Stronger appetite control and visible body-composition changes.
Month 5 1.5 mg → 1.75 mg weekly 60 → 70 units Continued progress with improved energy and steady results.
Month 6+ 2.0 mg → 2.5 mg weekly 80 → 100 units Maintenance phase — your optimal dose for long-term weight management.
Month 1
Weekly Dose (mg)
0.2 mg weekly
Units (for reference)
20 units
What to Expect
Your starter dose. Appetite may begin to decrease, and your body starts adjusting.
Month 2
Weekly Dose (mg)
0.25 mg → 0.5 mg weekly
Units (for reference)
10 → 20 units
What to Expect
You may notice smaller portions and steadier appetite control.
Month 3
Weekly Dose (mg)
1.0 mg weekly
Units (for reference)
40 units
What to Expect
More consistent weight loss and appetite regulation.
Month 4
Weekly Dose (mg)
1.5 mg → 1.75 mg weekly
Units (for reference)
60 → 70 units
What to Expect
Stronger appetite control and visible body-composition changes.
Month 5
Weekly Dose (mg)
1.5 mg → 1.75 mg weekly
Units (for reference)
60 → 70 units
What to Expect
Continued progress with improved energy and steady results.
Month 6+
Weekly Dose (mg)
2.0 mg → 2.5 mg weekly
Units (for reference)
80 → 100 units
What to Expect
Maintenance phase — your optimal dose for long-term weight management.

How It Feels Along the Way

  • Early weeks: Mild nausea, bloating, or fatigue as your body adapts.

  • Middle weeks: Reduced cravings, smaller meals, noticeable weight changes.

  • Later weeks: Steady weight loss — many patients see 10–15% of total body weight reduced when paired with healthy eating and activity.

Tips for Success

- Eat slowly and stop when full
- Focus on protein-rich, balanced meals
- Drink plenty of water to support digestion
- Report any side effects — your provider can adjust your dose if needed

Why Choose HolaVida

At HolaVida, we make semaglutide treatment simple, safe, and affordable:

  • 100% online care — no clinic visits required

  • Lowest prices on the market$129/month quarterly or $133/month month-to-month

  • Personalized support — ongoing coaching to help you stay on track

👉 Start your online consultation today and begin your GLP-1 weight-loss plan with confidence.

Related Conditions

GLP-1
October 24, 2025

Why Weight Loss Looks Different for Everyone on GLP-1s

If you’ve ever compared your progress to someone else’s and wondered why your results look different—don’t worry, that’s completely normal. Weight loss on GLP-1s, with medications like Semaglutide or Tirzepatide, is a deeply personal experience, shaped by everything from your genetics and hormones to your sleep, stress, and nutrition habits.

GLP-1
October 24, 2025

The Science Behind GLP-1s: How These Medications Actually Work

Intro: GLP-1 medications like Semaglutide and Tirzepatide have become game-changers in modern healthcare—but how do they really work? The answer lies in your body’s natural biology. GLP-1 stands for glucagon-like peptide-1, a hormone your gut releases after eating that tells your brain, “I’m full.” It also helps regulate blood sugar and digestion.

GLP-1
October 24, 2025

What to Expect During Your First Month on GLP-1s

Intro: Starting GLP-1 medications like Semaglutide or Tirzepatide is an exciting step toward better health—but it can also come with a few unknowns. During the first month, your body is adjusting to a new rhythm: your appetite changes, your digestion slows, and your energy may fluctuate as your system learns to balance blood sugar and hunger cues.