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If you're exploring GLP-1 treatment for weight loss, you've likely come across two names: semaglutide and tirzepatide. Both are effective, FDA-approved medications — but they work in slightly different ways and may suit different patients.

How Each Medication Works

Semaglutide

Semaglutide is a GLP-1 receptor agonist that mimics a single hormone to reduce appetite, slow digestion, and improve blood sugar control. Clinical trials show average weight loss of 10–15% of body weight.

Tirzepatide

Tirzepatide is a dual GLP-1/GIP receptor agonist — acting on two hormones simultaneously. This dual mechanism generally produces stronger appetite suppression and metabolic support, with clinical trials showing average weight loss of 15–20% or more.

Key Differences at a Glance

Mechanism: Semaglutide acts on one hormone; tirzepatide acts on two.

Average weight loss: Semaglutide: 10–15%; Tirzepatide: 15–20%+.

Price at HolaVida: Semaglutide from $129/month; Tirzepatide from $190/month.

Which Should You Choose?

The right medication depends on your health history, goals, budget, and how your body responds. Your licensed HolaVida provider will review your intake and help determine the most appropriate treatment.

Both semaglutide and tirzepatide plans at HolaVida include licensed provider care, personalized dosing, and coaching — at transparent, affordable prices.

Ready to get started? Review our plans and begin your consultation today